IL6ST (Human) Recombinant Protein
产品名称： IL6ST (Human) Recombinant Protein
英文名称： IL6ST (Human) Recombinant Protein
产品编号： H00003572-G01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human IL6ST full-length ORF (ADR83277.1) recombinant protein without tag.
- Sequence:
- MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDRGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYVATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEGMPKSYLPQTVRQGGYMPQ
- Theoretical MW (kDa):
- 101
- Form:
- Liquid
- Preparation Method:
- in vitro wheat germ expression system with proprietary liposome technology
- Storage Buffer:
- 25 mM Tris-HCl of pH8.0 containing 2% glycerol.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Note:
- Best use within three months from the date of receipt of this protein.
- Publication Reference
- 1.
- Production and partial purification of membrane proteins using a liposome-supplemented wheat cell-free translation system.
Nozawa A, Ogasawara T, Matsunaga S, Iwasaki T, Sawasaki T, Endo Y. BMC Biotechnol. 2011 Apr 11;11:35.
- Application Image
- Antibody Production
- Functional Study
- Compound Screening
- Entrez GeneID:
- 3572
- GeneBank Accession#:
- HQ258523.1
- Protein Accession#:
- ADR83277.1
- Gene Name:
- IL6ST
- Gene Alias:
- CD130,CDw130,GP130,GP130-RAPS,IL6R-beta
- Gene Description:
- interleukin 6 signal transducer (gp130, oncostatin M receptor)
- Omim ID:
- 600694
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
- Other Designations:
- CD130 antigen,IL6ST nirs variant 3,OTTHUMP00000122545,gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form,gp130 transducer chain,interleukin 6 signal transducer,interleukin receptor beta chain,membrane glycoprotein gp130,oncostatin M
- Related Disease
- Arthritis, Rheumatoid
- Atherosclerosis
- Cardiovascular Diseases
- Celiac Disease
- Chronic Disease
- Coronary Disease
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hodgkin Disease
- Hyperandrogenism
- Hypertension
- Lymphoproliferative Disorders
- Metabolic Syndrome X
- Multiple Myeloma
- Myocardial Infarction
- Obesity
- Obesity