XRCC5 monoclonal antibody, clone F3
产品名称： XRCC5 monoclonal antibody, clone F3
英文名称： XRCC5 monoclonal antibody, clone F3
产品编号： MAB7979
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant XRCC5.
- Immunogen:
- Recombinant protein corresponding to human XRCC5.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In phosphate-buffered solution, pH 7.2 (50% glycerol, 0.09% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (15 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Immunofluorescence
- Entrez GeneID:
- 7520
- Gene Name:
- XRCC5
- Gene Alias:
- FLJ39089,KARP-1,KARP1,KU80,KUB2,Ku86,NFIV
- Gene Description:
- X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
- Omim ID:
- 194364
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq
- Other Designations:
- ATP-dependent DNA helicase II,DNA repair protein XRCC5,Ku autoantigen, 80kDa,Ku86 autoantigen related protein 1,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kD),X-ray repair, comp
- Gene Pathway
- Related Disease
- Acute Disease
- Adenocarcinoma
- Ataxia telangiectasia
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Central Nervous System Neoplasms
- Colorectal Neoplasms
- DNA Damage
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Genital Neoplasms, Female
- Genomic Instability
- Glioma
- Head and Neck Neoplasms
- Kidney Failure, Chronic
- Leukemia, Myeloid