RASGRP3 (Human) Recombinant Protein (Q02)
产品名称: RASGRP3 (Human) Recombinant Protein (Q02)
英文名称: RASGRP3 (Human) Recombinant Protein (Q02)
产品编号: H00025780-Q02
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human RASGRP3 partial ORF ( NP_733772.1, 1 a.a. - 99 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MGSSGLGKAATLDELLCTCIEMFDDNGELDNSYLPRIVLLMHRWYLSSTELAEKLLCMYRNATGESCNEFRLKICYFMRYWILKFPAEFNLDLGLIRMT
- Theoretical MW (kDa):
- 36.63
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 25780
- GeneBank Accession#:
- NM_170672
- Protein Accession#:
- NP_733772.1
- Gene Name:
- RASGRP3
- Gene Alias:
- GRP3,KIAA0846
- Gene Description:
- RAS guanyl releasing protein 3 (calcium and DAG-regulated)
- Omim ID:
- 609531
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM
- Other Designations:
- guanine nucleotide exchange factor for Rap1