RPN2 (N-term) Peptide
产品名称： RPN2 (N-term) Peptide
英文名称： RPN2 (N-term) Peptide
产品编号： P1088
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of RPN2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human RPN2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties.
Kelleher DJ, Karaoglu D, Mandon EC, Gilmore R.Mol Cell. 2003 Jul;12(1):101-11.
- 2.
- Retention of subunits of the oligosaccharyltransferase complex in the endoplasmic reticulum.
Fu J, Kreibich G.J Biol Chem. 2000 Feb 11;275(6):3984-90.
- 3.
- Mapping of the ribophorin II (RPN II) gene to human chromosome 20q12-q13.1 by in-situ hybridization.
Loffler C, Rao VV, Hansmann I.Hum Genet. 1991 Jun;87(2):221-2.
- Applications
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with RPN2 polyclonal antibody (Cat # PAB4311) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . HC = hepatocarcinoma .
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- ELISA
- Entrez GeneID:
- 6185
- Protein Accession#:
- RIB2_HUMAN
- Gene Name:
- RPN2
- Gene Alias:
- RIBIIR,RPN-II,RPNII,SWP1
- Gene Description:
- ribophorin II
- Omim ID:
- 180490
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to the yeast oligosaccharyl transferase subunit SWP1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit
- Gene Pathway
- Related Disease