Anti-HLA-DPB1 Polyclonal Antibody

品牌：solarbio | 货号：K002774P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002774P-50ul	solarbio	50ul	960.00元
K002774P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-HLA-DPB1 Polyclonal Antibody
别名	DPB1;HLA-DP;HLA-DP1B;HLA-DPB
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human Mouse Rat
蛋白分子量	29kDa
Gene ID	3115
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human HLA-DPB1
性状	液体
Public Immunogen Range	Recombinant protein of human HLA-DPB1
Subcellular Locations	Cell membrane Endoplasmic reticulum membrane Endosome membrane Golgi apparatus Lysosome membrane Single-pass type I membrane protein trans-Golgi network membrane
Swiss Prot	P04440
克隆类型	Polyclonal Antibody
背景资料	HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.