PARP1 polyclonal antibody
产品名称： PARP1 polyclonal antibody
英文名称： PARP1 polyclonal antibody
产品编号： PAB11729
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PARP1.
- Immunogen:
- A synthetic peptide corresponding to N-terminus of human PARP1.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 116
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Immunoaffinity purification
- Concentration:
- Lot specific
- Storage Buffer:
- In 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide)
- Storage Instruction:
- Store at 4°C.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 142
- Gene Name:
- PARP1
- Gene Alias:
- ADPRT,ADPRT1,PARP,PARP-1,PPOL,pADPRT-1
- Gene Description:
- poly (ADP-ribose) polymerase 1
- Omim ID:
- 173870
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq
- Other Designations:
- ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase),ADP-ribosyltransferase NAD(+),OTTHUMP00000035663,poly (ADP-ribose) polymerase family, member 1,poly(ADP-ribose) polymerase,poly(ADP-ribose) synthetase,poly(ADP-ribosyl)transferase
- Gene Pathway
- Related Disease
- Acute Disease
- Adenocarcinoma
- Adenomyoma
- Alzheimer Disease
- Alzheimer disease
- Arthritis
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Ataxia telangiectasia
- Brain Injuries
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma, Ductal
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Chronic Disease