STAT6 MaxPab rabbit polyclonal antibody (D01)
产品名称： STAT6 MaxPab rabbit polyclonal antibody (D01)
英文名称： STAT6 MaxPab rabbit polyclonal antibody (D01)
产品编号： H00006778-D01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human STAT6 protein.
- Immunogen:
- STAT6 (NP_003144.3, 1 a.a. ~ 847 a.a) full-length human protein.
- Sequence:
- MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDTVQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMPFHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALAMLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQEVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLRFLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALFKNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDNNAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMDLRANPSW
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Storage Buffer:
- No additive
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- STAT6 MaxPab rabbit polyclonal antibody. Western Blot analysis of STAT6 expression in mouse brain.
- Protocol Download
- Western Blot (Cell lysate)
- STAT6 MaxPab rabbit polyclonal antibody. Western Blot analysis of STAT6 expression in HeLa.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of STAT6 expression in transfected 293T cell line (H00006778-T02) by STAT6 MaxPab polyclonal antibody.
Lane 1: STAT6 transfected lysate(94.1 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunoprecipitation
- Immunoprecipitation of STAT6 transfected lysate using anti-STAT6 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with STAT6 purified MaxPab mouse polyclonal antibody (B01P) (H00006778-B01P).
- Protocol Download
- Entrez GeneID:
- 6778
- GeneBank Accession#:
- NM_003153.3
- Protein Accession#:
- NP_003144.3
- Gene Name:
- STAT6
- Gene Alias:
- D12S1644,IL-4-STAT,STAT6B,STAT6C
- Gene Description:
- signal transducer and activator of transcription 6, interleukin-4 induced
- Omim ID:
- 601512
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. [provided by RefSeq
- Other Designations:
- STAT, interleukin4-induced,signal transducer and activator of transcription 6,transcription factor IL-4 STAT
- Gene Pathway
- Related Disease
- Anaphylaxis
- Arthritis, Rheumatoid
- Ascariasis
- Asthma
- Asthma
- Birth Weight
- Breast cancer
- Breast Neoplasms
- Bronchial Hyperreactivity
- Bronchiolitis, Viral
- Cardiovascular Diseases
- Colitis, Ulcerative
- Confusion
- Crohn Disease
- Crohn's disease
- Dermatitis, Atopic
- Diabetes Mellitus, Type 2
- Disease Progression
- Drug Hypersensitivity